DOI
https://doi.org/10.47689/2181-3663-vol4-iss4-pp131-139Kalit so‘zlar
appendiks flegmonasi , murakkab appenditsit , konservativ davolash , interval appendektomiya , kompyuter tomografiyasi , laparoskopik jarrohlik , tasvir asosida drenaj , antibiotik terapiyasi , mikrobiom , diagnostik qiyinchiliklarAnnotasiya
Appendiks flegmonasi o‘tkir appenditsitning murakkab shakli bo‘lib, u organizmning himoya mexanizmlari mahalliy perforatsiyani muvaffaqiyatli cheklaganda hosil bo‘ladigan yallig‘lanish infiltrati bilan tavsiflanadi. Ushbu jarayon odatda o‘tkazuv yo‘lining to‘silib qolishi, ishemiya, nekroz va keyingi yorilish natijasida rivojlanadi. Flegmon va abscessni farqlash katta diagnostik muammo bo‘lib, bu tanlangan davolash taktikasi va klinik natijalarga bevosita ta’sir qiladi. Kompyuter tomografiyasi (KT) asosiy tashxis vositasi hisoblanadi, u aniq chegaralanmagan yallig‘lanish massalarini, ammo suyuqlik to‘plangan bo‘shliqlarsiz holatni ko‘rsatadi. Davolash yondashuvlari hanuz bahsli bo‘lib, ular konservativ boshqaruv (antibiotiklar, kuzatuv va ehtimoliy interval appendektomiya) hamda erta jarrohlik aralashuvi o‘rtasida farqlanadi. Zamonaviy dalillar konservativ yondashuvni afzal ko‘rsatadi, chunki u asoratlar sonini kamaytiradi va shoshilinch operatsiya ehtimolini pasaytiradi. Shu bilan birga, laparoskopik jarrohlikning rivojlanishi ayrim holatlarda erta appendektomiyaga qiziqishni qayta tikladi. Interval appendektomiyaning zaruriyati qayta ko‘rib chiqilmoqda — hozirda tanlab o‘tkaziladigan yondashuv afzal hisoblanadi. Tasvir nazorati ostida drenaj abscesslarni boshqarishda muhim rol o‘ynaydi, biroq u muvaffaqiyatsizlik xavfi bilan bog‘liq. Antibiotiklarni to‘g‘ri tanlash, davolash muddatini aniqlash va appendiks mikrobiomining roli bo‘yicha yangi ma’lumotlar kasallikni chuqurroq tushunishga yordam bermoqda. Diagnostika aniqligi va davolash standartlaridagi bo‘shliqlar kelajakda yirik, ko‘p markazli randomizatsiyalangan tadqiqotlar o‘tkazishni talab qiladi, bu esa appendiks flegmonasini boshqarish bo‘yicha dalillarga asoslangan klinik tavsiyalar ishlab chiqish imkonini beradi.
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