DOI
https://doi.org/10.47689/2181-3663-vol4-iss4-pp110-118Keywords
post-COVID syndrome , children , bronchopneumonia , clinical courseAbstract
Recent literature has reported isolated cases of the clinical course of post-COVID syndrome in children, including multiple organ involvement, autoimmune lesions, and pronounced changes in the immune system. The long-term consequences of coronavirus infection in children remain poorly studied.
Objective: To investigate the clinical features of bronchopneumonia in post-COVID syndrome in children.
Materials and methods: We observed 179 patients: 61 with "long COVID" (symptom duration more than 4 but less than 12 weeks), 68 with CPS (chronic post-COVID syndrome; over 12 weeks from disease onset according to ICD-10), and 50 children with CAP (community-acquired pneumonia) of unknown etiology aged 1 to 12 years. All children were admitted to the Termez City Children's Medical Center with bronchopneumonia and hospitalized in the pulmonology department and ICU. ELISA for S-RBD SARS-CoV-2 IgG was considered positive at a value > 1 IU/ml.
Results and discussion: Bronchopneumonia in long COVID mainly presented with moderate severity, dyspnea, subcostal retractions during breathing, and often a segmental form of bronchopneumonia was diagnosed. CPS was characterized by a high frequency of severe bronchopneumonia, central cyanosis, severe respiratory failure (head bobbing), pronounced signs of CNS intoxication (temperature decrease to 35°C and below, increased pulse rate), and was often diagnosed as interstitial pneumonia. Prolonged manifestation of CPS was ultimately characterized by autoimmune pathology and juvenile rheumatoid arthritis, gastrointestinal diseases and diarrhea, Guillain-Barré syndrome, and polyradiculoneuropathy. In long COVID, the development of a septic process with generalized damage to various organs and systems and Stevens-Johnson syndrome was noted.
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